The impact of DNA damage response gene polymorphisms on therapeutic outcomes in late stage ovarian cancer

Late stage epithelial ovarian cancer has a dismal prognosis. Identification of pharmacogenomic markers (i.e. polymorphisms) to stratify patients to optimize individual therapy is of paramount importance. We here report the retrospective analysis of polymorphisms in 5 genes (ATM, ATR, Chk1, Chk2 and...

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Detalles Bibliográficos
Autores principales: Guffanti, F., Fruscio, R., Rulli, E., Damia, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131275/
https://www.ncbi.nlm.nih.gov/pubmed/27905519
http://dx.doi.org/10.1038/srep38142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131275/
https://www.ncbi.nlm.nih.gov/pubmed/27905519
http://dx.doi.org/10.1038/srep38142

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