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The impact of DNA damage response gene polymorphisms on therapeutic outcomes in late stage ovarian cancer

Late stage epithelial ovarian cancer has a dismal prognosis. Identification of pharmacogenomic markers (i.e. polymorphisms) to stratify patients to optimize individual therapy is of paramount importance. We here report the retrospective analysis of polymorphisms in 5 genes (ATM, ATR, Chk1, Chk2 and...

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Detalles Bibliográficos
Autores principales:	Guffanti, F., Fruscio, R., Rulli, E., Damia, G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131275/ https://www.ncbi.nlm.nih.gov/pubmed/27905519 http://dx.doi.org/10.1038/srep38142

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