Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation

The pathogenesis of pain in lumbar disc herniation (LDH) remains poorly understood. We have recently demonstrated that voltage-gated sodium channels (VGSCs) in dorsal root ganglion (DRG) neurons were sensitized in a rat model of LDH. However, the detailed molecular mechanism for sensitization of VGS...

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Detalles Bibliográficos
Autores principales: Yan, Jun, Hu, Shufen, Zou, Kang, Xu, Min, Wang, Qianliang, Miao, Xiuhua, Yu, Shan Ping, Xu, Guang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131276/
https://www.ncbi.nlm.nih.gov/pubmed/27905525
http://dx.doi.org/10.1038/srep38188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131276/
https://www.ncbi.nlm.nih.gov/pubmed/27905525
http://dx.doi.org/10.1038/srep38188

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