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Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation
The pathogenesis of pain in lumbar disc herniation (LDH) remains poorly understood. We have recently demonstrated that voltage-gated sodium channels (VGSCs) in dorsal root ganglion (DRG) neurons were sensitized in a rat model of LDH. However, the detailed molecular mechanism for sensitization of VGS...
Autores principales: | Yan, Jun, Hu, Shufen, Zou, Kang, Xu, Min, Wang, Qianliang, Miao, Xiuhua, Yu, Shan Ping, Xu, Guang-Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131276/ https://www.ncbi.nlm.nih.gov/pubmed/27905525 http://dx.doi.org/10.1038/srep38188 |
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