Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine

The demand for improved pertussis vaccines is urgent due to the resurgence of whooping cough. A deeper understanding of the mode of action of pertussis vaccines is required to achieve this improvement. The vaccine-induced effects of a candidate outer membrane vesicle vaccine (omvPV) and a classical...

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Detalles Bibliográficos
Autores principales: Raeven, René H. M., Brummelman, Jolanda, Pennings, Jeroen L. A., van der Maas, Larissa, Tilstra, Wichard, Helm, Kina, van Riet, Elly, Jiskoot, Wim, van Els, Cécile A. C. M., Han, Wanda G. H., Kersten, Gideon F. A., Metz, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131296/
https://www.ncbi.nlm.nih.gov/pubmed/27905535
http://dx.doi.org/10.1038/srep38240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131296/
https://www.ncbi.nlm.nih.gov/pubmed/27905535
http://dx.doi.org/10.1038/srep38240

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