The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity

Mechanical integration of the nucleus with the extracellular matrix (ECM) is established by linkage between the cytoskeleton and the nucleus. This integration is hypothesized to mediate sensing of ECM rigidity, but parsing the function of nucleus-cytoskeleton linkage from other mechanisms has remain...

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Detalles Bibliográficos
Autores principales: Alam, Samer G., Zhang, Qiao, Prasad, Nripesh, Li, Yuan, Chamala, Srikar, Kuchibhotla, Ram, KC, Birendra, Aggarwal, Varun, Shrestha, Shristi, Jones, Angela L., Levy, Shawn E., Roux, Kyle J., Nickerson, Jeffrey A., Lele, Tanmay P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131312/
https://www.ncbi.nlm.nih.gov/pubmed/27905489
http://dx.doi.org/10.1038/srep38063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131312/
https://www.ncbi.nlm.nih.gov/pubmed/27905489
http://dx.doi.org/10.1038/srep38063

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