Cargando…

Protein-peptide molecular docking with large-scale conformational changes: the p53-MDM2 interaction

Protein-peptide interactions are often associated with large-scale conformational changes that are difficult to study either by classical molecular modeling or by experiment. Recently, we have developed the CABS-dock method for flexible protein-peptide docking that enables large-scale rearrangements...

Descripción completa

Detalles Bibliográficos
Autores principales: Ciemny, Maciej Pawel, Debinski, Aleksander, Paczkowska, Marta, Kolinski, Andrzej, Kurcinski, Mateusz, Kmiecik, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131342/
https://www.ncbi.nlm.nih.gov/pubmed/27905468
http://dx.doi.org/10.1038/srep37532