Limitations of MIC as sole metric of pharmacodynamic response across the range of antimicrobial susceptibilities within a single bacterial species

The minimum inhibitory concentration (MIC) of an antimicrobial drug for a bacterial pathogen is used as a measure of the bacterial susceptibility to the drug. However, relationships between the antimicrobial concentration, bacterial susceptibility, and the pharmacodynamic (PD) inhibitory effect on t...

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Detalles Bibliográficos
Autores principales: Wen, Xuesong, Gehring, Ronette, Stallbaumer, Andrea, Riviere, Jim E., Volkova, Victoriya V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131373/
https://www.ncbi.nlm.nih.gov/pubmed/27905408
http://dx.doi.org/10.1038/srep37907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131373/
https://www.ncbi.nlm.nih.gov/pubmed/27905408
http://dx.doi.org/10.1038/srep37907

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