Cargando…
Limitations of MIC as sole metric of pharmacodynamic response across the range of antimicrobial susceptibilities within a single bacterial species
The minimum inhibitory concentration (MIC) of an antimicrobial drug for a bacterial pathogen is used as a measure of the bacterial susceptibility to the drug. However, relationships between the antimicrobial concentration, bacterial susceptibility, and the pharmacodynamic (PD) inhibitory effect on t...
Autores principales: | Wen, Xuesong, Gehring, Ronette, Stallbaumer, Andrea, Riviere, Jim E., Volkova, Victoriya V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131373/ https://www.ncbi.nlm.nih.gov/pubmed/27905408 http://dx.doi.org/10.1038/srep37907 |
Ejemplares similares
-
Variation in fluoroquinolone pharmacodynamic parameter values among isolates of two bacterial pathogens of bovine respiratory disease
por: Wen, Xuesong, et al.
Publicado: (2018) -
Mathematical modeling of the ‘inoculum effect': six applicable models and the MIC advancement point concept
por: Salas, Jessica R, et al.
Publicado: (2020) -
What’s the Matter with MICs: Bacterial Nutrition, Limiting Resources, and Antibiotic Pharmacodynamics
por: Berryhill, Brandon A., et al.
Publicado: (2023) -
Limitations of Antibiotic MIC-Based PK-PD Metrics: Looking Back to Move Forward
por: Landersdorfer, Cornelia B., et al.
Publicado: (2021) -
Pharmacokinetics and Pharmacodynamics of Tildipirosin Against Pasteurella multocida in a Murine Lung Infection Model
por: Zeng, Dongping, et al.
Publicado: (2018)