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Asperterpenes A and B, two unprecedented meroterpenoids from Aspergillus terreus with BACE1 inhibitory activities

Asperterpenes A (1) and B (2), two 3,5-dimethylorsellinic acid-based meroterpenoids that contain a unique β-oriented Me-21 with an unprecedented 1,2,5-trimethyl-4,9-dioxobicyclo[3.3.1]non-2-ene-3-carboxylic acid moiety, were obtained from Aspergillus terreus in very limited amounts of 3.6 mg and 1.8...

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Detalles Bibliográficos
Autores principales: Qi, Changxing, Bao, Jian, Wang, Jianping, Zhu, Hucheng, Xue, Yongbo, Wang, Xiaochuan, Li, Hua, Sun, Weiguang, Gao, Weixi, Lai, Yongji, Chen, Jian-Guo, Zhang, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131395/
https://www.ncbi.nlm.nih.gov/pubmed/28042460
http://dx.doi.org/10.1039/c6sc02464e