miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans

BACKGROUND: In mammals, the IGF-1 pathway affects the phenotype of aging. Since the function of the immune system is modulated by IGF-1, it is plausible that immunosenescence might in part result from altered control by this pathway. We therefore examined whether the expression of IGF-1R, FOXO1, and...

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Detalles Bibliográficos
Autores principales: Budzinska, Monika, Owczarz, Magdalena, Pawlik-Pachucka, Eliza, Roszkowska-Gancarz, Malgorzata, Slusarczyk, Przemyslaw, Puzianowska-Kuznicka, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131432/
https://www.ncbi.nlm.nih.gov/pubmed/27903254
http://dx.doi.org/10.1186/s12877-016-0379-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131432/
https://www.ncbi.nlm.nih.gov/pubmed/27903254
http://dx.doi.org/10.1186/s12877-016-0379-y

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