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The ER stress regulator Bip mediates cadmium-induced autophagy and neuronal senescence

Autophagy is protective in cadmium (Cd)-induced oxidative damage. Endoplasmic reticulum (ER) stress has been shown to induce autophagy in a process requiring the unfolded protein response signalling pathways. Cd treatment significantly increased senescence in neuronal cells, which was aggravated by...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Yuan, Yan, Zou, Hui, Yang, Jinlong, Zhao, Shiwen, Ma, Yonggang, Wang, Yi, Bian, Jianchun, Liu, Xuezhong, Gu, Jianhong, Liu, Zongping, Zhu, Jiaqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131476/
https://www.ncbi.nlm.nih.gov/pubmed/27905509
http://dx.doi.org/10.1038/srep38091