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Remarkable alterations of Nav1.6 in reactive astrogliosis during epileptogenesis

Voltage-gated sodium channels (VGSCs) play a vital role in controlling neuronal excitability. Nav1.6 is the most abundantly expressed VGSCs subtype in the adult central nervous system and has been found to contribute to facilitate the hyperexcitability of neurons after electrical induction of status...

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Detalles Bibliográficos
Autores principales: Zhu, Hongyan, Zhao, Yuxiao, Wu, Hao, Jiang, Nan, Wang, Ziyi, Lin, Weide, Jin, Jiahui, Ji, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131488/
https://www.ncbi.nlm.nih.gov/pubmed/27905510
http://dx.doi.org/10.1038/srep38108