Analysis of RNA expression of normal and cancer tissues reveals high correlation of COP9 gene expression with respiratory chain complex components

BACKGROUND: The COP9 signalosome, composed of eight subunits, is implicated in cancer genetics with its deneddylase activity to modulate cellular concentration of oncogenic proteins such as IkB and TGFβ. However, its function in the normal cell physiology remains elusive. Primarily focusing on gene...

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Detalles Bibliográficos
Autores principales: Wicker, Christina A., Izumi, Tadahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131501/
https://www.ncbi.nlm.nih.gov/pubmed/27903243
http://dx.doi.org/10.1186/s12864-016-3313-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131501/
https://www.ncbi.nlm.nih.gov/pubmed/27903243
http://dx.doi.org/10.1186/s12864-016-3313-y

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