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Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) patients in military settings can be exposed to prolonged periods of hypobaria (HB) during aeromedical evacuation. Hypobaric exposure, even with supplemental oxygen to prevent hypoxia, worsens outcome after experimental TBI, in part by increasing neuroinflamm...

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Detalles Bibliográficos
Autores principales: Skovira, Jacob W., Wu, Junfang, Matyas, Jessica J., Kumar, Alok, Hanscom, Marie, Kabadi, Shruti V., Fang, Raymond, Faden, Alan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131508/
https://www.ncbi.nlm.nih.gov/pubmed/27903275
http://dx.doi.org/10.1186/s12974-016-0769-2