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Insight into the ERVK Integrase – Propensity for DNA Damage

Retroviruses create permanently integrated proviruses that exist in the host genome. Retroviral genomes encode for functionally conserved gag, pro, pol, and env regions, as well as integrase (IN), which is required for retroviral integration. IN mediates viral genome insertion through 3′ end process...

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Detalles Bibliográficos
Autores principales: Bray, Samantha, Turnbull, Matthew, Hebert, Sherry, Douville, Renée N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131560/
https://www.ncbi.nlm.nih.gov/pubmed/27990140
http://dx.doi.org/10.3389/fmicb.2016.01941