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Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques

OBJECTIVE: Resting CD4(+) T cells have been recognized as the major cell reservoir of latent HIV-1 during antiretroviral therapy (ART). Using an simian immunodeficiency virus (SIV)/macaque model for AIDS and HIV-related neurocognitive disorders we assessed the contribution of the brain to viral late...

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Detalles Bibliográficos
Autores principales: Gama, Lucio, Abreu, Celina M., Shirk, Erin N., Price, Sarah L., Li, Ming, Laird, Greg M., Pate, Kelly A. Metcalf, Wietgrefe, Stephen W., O’Connor, Shelby L., Pianowski, Luiz, Haase, Ashley T., Van Lint, Carine, Siliciano, Robert F., Clements, Janice E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131686/
https://www.ncbi.nlm.nih.gov/pubmed/27898590
http://dx.doi.org/10.1097/QAD.0000000000001267