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Antitumor activity of recombinant RGD-IFN-α2a-core fusion protein in vitro

Interferon (IFN) regulates immune responses and antitumor activity. Arginine–glycine–aspartic acid (RGD) peptides can specifically bind to integrin α(v)β(3), a transmembrane receptor that is highly expressed on the surface of various cancer cells. In this study, we expressed recombinant RGD-IFN-α2a-...

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Detalles Bibliográficos
Autores principales: Wen, Zhengwei, Jia, Qunying, Kang, Xiaojuan, Lou, Yongliang, Zou, Lilin, Yang, Jifeng, Gao, Jimin, Han, Liping, Li, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131691/
https://www.ncbi.nlm.nih.gov/pubmed/27759573
http://dx.doi.org/10.1097/CAD.0000000000000421