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Antitumor activity of recombinant RGD-IFN-α2a-core fusion protein in vitro
Interferon (IFN) regulates immune responses and antitumor activity. Arginine–glycine–aspartic acid (RGD) peptides can specifically bind to integrin α(v)β(3), a transmembrane receptor that is highly expressed on the surface of various cancer cells. In this study, we expressed recombinant RGD-IFN-α2a-...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131691/ https://www.ncbi.nlm.nih.gov/pubmed/27759573 http://dx.doi.org/10.1097/CAD.0000000000000421 |