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Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly
In cytoplasm, the survival of motor neuron (SMN) complex delivers pre-small nuclear RNAs (pre-snRNAs) to the heptameric Sm ring for the assembly of the ring complex on pre-snRNAs at the conserved Sm site [A(U)(4–6)G]. Gemin5, a WD40 protein component of the SMN complex, is responsible for recognizin...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131778/ https://www.ncbi.nlm.nih.gov/pubmed/27881600 http://dx.doi.org/10.1101/gad.288340.116 |