Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly

In cytoplasm, the survival of motor neuron (SMN) complex delivers pre-small nuclear RNAs (pre-snRNAs) to the heptameric Sm ring for the assembly of the ring complex on pre-snRNAs at the conserved Sm site [A(U)(4–6)G]. Gemin5, a WD40 protein component of the SMN complex, is responsible for recognizin...

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Detalles Bibliográficos
Autores principales: Xu, Chao, Ishikawa, Hideaki, Izumikawa, Keiichi, Li, Li, He, Hao, Nobe, Yuko, Yamauchi, Yoshio, Shahjee, Hanief M., Wu, Xian-Hui, Yu, Yi-tao, Isobe, Toshiaki, Takahashi, Nobuhiro, Min, Jinrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131778/
https://www.ncbi.nlm.nih.gov/pubmed/27881600
http://dx.doi.org/10.1101/gad.288340.116

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