Improved assembly of noisy long reads by k-mer validation
Genome assembly depends critically on read length. Two recent technologies, from Pacific Biosciences (PacBio) and Oxford Nanopore, produce read lengths >20 kb, which yield de novo genome assemblies with vastly greater contiguity than those based on Sanger, Illumina, or other technologies. However...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131822/ https://www.ncbi.nlm.nih.gov/pubmed/27831497 http://dx.doi.org/10.1101/gr.209247.116 |