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Improved assembly of noisy long reads by k-mer validation

Genome assembly depends critically on read length. Two recent technologies, from Pacific Biosciences (PacBio) and Oxford Nanopore, produce read lengths >20 kb, which yield de novo genome assemblies with vastly greater contiguity than those based on Sanger, Illumina, or other technologies. However...

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Detalles Bibliográficos
Autores principales:	Carvalho, Antonio Bernardo, Dupim, Eduardo G., Goldstein, Gabriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131822/ https://www.ncbi.nlm.nih.gov/pubmed/27831497 http://dx.doi.org/10.1101/gr.209247.116

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