Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles

Active neurons increase their energy supply by dilating nearby arterioles and capillaries. This neurovascular coupling underlies BOLD functional imaging signals, but its mechanism is controversial. Canonically, neurons release glutamate to activate metabotropic glutamate receptors (mGluR5) on astroc...

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Detalles Bibliográficos
Autores principales: Mishra, Anusha, Reynolds, James P., Chen, Yang, Gourine, Alexander V., Rusakov, Dmitri A., Attwell, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131849/
https://www.ncbi.nlm.nih.gov/pubmed/27775719
http://dx.doi.org/10.1038/nn.4428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131849/
https://www.ncbi.nlm.nih.gov/pubmed/27775719
http://dx.doi.org/10.1038/nn.4428

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