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Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles
Active neurons increase their energy supply by dilating nearby arterioles and capillaries. This neurovascular coupling underlies BOLD functional imaging signals, but its mechanism is controversial. Canonically, neurons release glutamate to activate metabotropic glutamate receptors (mGluR5) on astroc...
Autores principales: | Mishra, Anusha, Reynolds, James P., Chen, Yang, Gourine, Alexander V., Rusakov, Dmitri A., Attwell, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131849/ https://www.ncbi.nlm.nih.gov/pubmed/27775719 http://dx.doi.org/10.1038/nn.4428 |
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