Model‐Based Assessment of Alternative Study Designs in Pediatric Trials. Part I: Frequentist Approaches

Alternative designs can increase the feasibility of pediatric trials when compared to classical parallel designs (PaD). In this work we present a model‐based approach based on clinical trial simulations for the comparison of PaD with the alternative sequential, crossover, and randomized withdrawal (...

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Detalles Bibliográficos
Autores principales: Smania, G, Baiardi, P, Ceci, A, Magni, P, Cella, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131885/
https://www.ncbi.nlm.nih.gov/pubmed/27300083
http://dx.doi.org/10.1002/psp4.12083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131885/
https://www.ncbi.nlm.nih.gov/pubmed/27300083
http://dx.doi.org/10.1002/psp4.12083

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