Structural and Functional Recovery of Sensory Cilia in C. elegans IFT Mutants upon Aging

The majority of cilia are formed and maintained by the highly conserved process of intraflagellar transport (IFT). Mutations in IFT genes lead to ciliary structural defects and systemic disorders termed ciliopathies. Here we show that the severely truncated sensory cilia of hypomorphic IFT mutants i...

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Detalles Bibliográficos
Autores principales: Cornils, Astrid, Maurya, Ashish K., Tereshko, Lauren, Kennedy, Julie, Brear, Andrea G., Prahlad, Veena, Blacque, Oliver E., Sengupta, Piali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131903/
https://www.ncbi.nlm.nih.gov/pubmed/27906968
http://dx.doi.org/10.1371/journal.pgen.1006325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131903/
https://www.ncbi.nlm.nih.gov/pubmed/27906968
http://dx.doi.org/10.1371/journal.pgen.1006325

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