PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress

Maintaining genomic integrity during DNA replication is essential for cellular survival and for preventing tumorigenesis. Proliferating cell nuclear antigen (PCNA) functions as a processivity factor for DNA replication, and posttranslational modification of PCNA plays a key role in coordinating DNA...

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Detalles Bibliográficos
Autores principales: Jo, Ukhyun, Cai, Winson, Wang, Jingming, Kwon, Yoojin, D’Andrea, Alan D., Kim, Hyungjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131917/
https://www.ncbi.nlm.nih.gov/pubmed/27906959
http://dx.doi.org/10.1371/journal.pgen.1006465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131917/
https://www.ncbi.nlm.nih.gov/pubmed/27906959
http://dx.doi.org/10.1371/journal.pgen.1006465

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