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TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospective Cohort Study

BACKGROUND AND AIM: TP53 encodes p53, which has a crucial role in modulating genes that regulate defense against cancer development. This study investigated whether TP53 polymorphisms are associated with colorectal cancer (CRC) in patients with Lynch syndrome and whether TP53 interacts with lifestyl...

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Detalles Bibliográficos
Autores principales: Kamiza, Abram Bunya, Hsieh, Ling-Ling, Tang, Reiping, Chien, Huei-Tzu, Lai, Chih-Hsiung, Chiu, Li-Ling, Lo, Tsai-Ping, Hung, Kuan-Yi, You, Jeng-Fu, Wang, Wen-Chang, Hsiung, Chao A., Yeh, Chih-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131981/
https://www.ncbi.nlm.nih.gov/pubmed/27907203
http://dx.doi.org/10.1371/journal.pone.0167354