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Transfusional Iron Overload in a Cohort of Children with Sickle Cell Disease: Impact of Magnetic Resonance Imaging, Transfusion Method, and Chelation

BACKGROUND: Transfusions prevent a number of complications of sickle cell disease (SCD), but cause inevitable iron loading. With magnetic resonance imaging (MRI), liver iron can be monitored noninvasively. Erythrocytapheresis can limit iron loading and oral chelation provides a more tolerable altern...

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Detalles Bibliográficos
Autores principales: Stanley, Helen M., Friedman, David F., Webb, Jennifer, Kwiatkowski, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132054/
https://www.ncbi.nlm.nih.gov/pubmed/27100139
http://dx.doi.org/10.1002/pbc.26017