Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation

Oligodendrocyte progenitor cell (OPC) differentiation is an important therapeutic target to promote remyelination in multiple sclerosis (MS). We previously reported hyperphosphorylated and aggregated microtubule‐associated protein tau in MS lesions, suggesting its involvement in axonal degeneration....

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Detalles Bibliográficos
Autores principales: Ossola, Bernardino, Zhao, Chao, Compston, Alastair, Pluchino, Stefano, Franklin, Robin J. M., Spillantini, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132073/
https://www.ncbi.nlm.nih.gov/pubmed/26576485
http://dx.doi.org/10.1002/glia.22940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132073/
https://www.ncbi.nlm.nih.gov/pubmed/26576485
http://dx.doi.org/10.1002/glia.22940

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