Cargando…
Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation
Oligodendrocyte progenitor cell (OPC) differentiation is an important therapeutic target to promote remyelination in multiple sclerosis (MS). We previously reported hyperphosphorylated and aggregated microtubule‐associated protein tau in MS lesions, suggesting its involvement in axonal degeneration....
Autores principales: | Ossola, Bernardino, Zhao, Chao, Compston, Alastair, Pluchino, Stefano, Franklin, Robin J. M., Spillantini, Maria Grazia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132073/ https://www.ncbi.nlm.nih.gov/pubmed/26576485 http://dx.doi.org/10.1002/glia.22940 |
Ejemplares similares
-
The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice
por: Brelstaff, Jack, et al.
Publicado: (2015) -
The organization of microtubules and Tau in oligodendrocytes: Tau pathology in damaged oligodendrocytes
por: Torii, Tomohiro, et al.
Publicado: (2022) -
Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by
Microglia
por: Brelstaff, Jack, et al.
Publicado: (2018) -
Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors
por: Gautier, Hélène O. B., et al.
Publicado: (2015) -
Tau in Oligodendrocytes Takes Neurons in Sickness and in Health
por: LoPresti, Patrizia
Publicado: (2018)