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Effect of Cabotegravir on Cardiac Repolarization in Healthy Subjects

A randomized, partial‐blind, repeat‐dose, 3‐period crossover study (NCT02027454) assessed the effect of cabotegravir on QT interval in healthy subjects. To achieve a supratherapeutic dose, each subject received cabotegravir 150 mg (30 mg × 5 tablets) every 12 hours for a total of 3 doses over 2 days...

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Detalles Bibliográficos
Autores principales: Lou, Yu, Buchanan, Ann M., Chen, Shuguang, Ford, Susan L., Gould, Elizabeth, Margolis, David, Spreen, William R., Patel, Parul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132079/
https://www.ncbi.nlm.nih.gov/pubmed/27162089
http://dx.doi.org/10.1002/cpdd.272