Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium

Cytochrome P450 monooxygenases (P450s) are attractive enzymes for the pharmaceutical industry, in particular, for applications in steroidal drug synthesis. Here, we report a comprehensive functional and structural characterization of CYP109E1, a novel steroid‐converting cytochrome P450 enzyme identi...

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Detalles Bibliográficos
Autores principales: Jóźwik, Ilona K., Kiss, Flora M., Gricman, Łukasz, Abdulmughni, Ammar, Brill, Elisa, Zapp, Josef, Pleiss, Juergen, Bernhardt, Rita, Thunnissen, Andy‐Mark W. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132081/
https://www.ncbi.nlm.nih.gov/pubmed/27686671
http://dx.doi.org/10.1111/febs.13911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132081/
https://www.ncbi.nlm.nih.gov/pubmed/27686671
http://dx.doi.org/10.1111/febs.13911

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