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Ambroxol effects in glucocerebrosidase and α‐synuclein transgenic mice

OBJECTIVE: Gaucher disease is caused by mutations in the glucocerebrosidase 1 gene that result in deficiency of the lysosomal enzyme glucocerebrosidase. Both homozygous and heterozygous glucocerebrosidase 1 mutations confer an increased risk for developing Parkinson disease. Current estimates indica...

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Detalles Bibliográficos
Autores principales: Migdalska‐Richards, Anna, Daly, Liam, Bezard, Erwan, Schapira, Anthony H. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132106/
https://www.ncbi.nlm.nih.gov/pubmed/27859541
http://dx.doi.org/10.1002/ana.24790