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A global test for gene‐gene interactions based on random matrix theory

Statistical interactions between markers of genetic variation, or gene‐gene interactions, are believed to play an important role in the etiology of many multifactorial diseases and other complex phenotypes. Unfortunately, detecting gene‐gene interactions is extremely challenging due to the large num...

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Detalles Bibliográficos
Autores principales: Frost, H. Robert, Amos, Christopher I., Moore, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132142/
https://www.ncbi.nlm.nih.gov/pubmed/27386793
http://dx.doi.org/10.1002/gepi.21990