A Minimal, Unstrained S‐Allyl Handle for Pre‐Targeting Diels–Alder Bioorthogonal Labeling in Live Cells

The unstrained S‐allyl cysteine amino acid was site‐specifically installed on apoptosis protein biomarkers and was further used as a chemical handle and ligation partner for 1,2,4,5‐tetrazines by means of an inverse‐electron‐demand Diels–Alder reaction. We demonstrate the utility of this minimal han...

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Detalles Bibliográficos
Autores principales: Oliveira, Bruno L., Guo, Zijian, Boutureira, Omar, Guerreiro, Ana, Jiménez‐Osés, Gonzalo, Bernardes, Gonçalo J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132151/
https://www.ncbi.nlm.nih.gov/pubmed/27763724
http://dx.doi.org/10.1002/anie.201608438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132151/
https://www.ncbi.nlm.nih.gov/pubmed/27763724
http://dx.doi.org/10.1002/anie.201608438

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