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Multiple facets of p53 in senescence induction and maintenance

Cellular senescence is a state of durable cell cycle arrest with metabolic activities distinct from those of the proliferative state. Since senescence was originally reported to be induced by various genotoxic stressors, such as telomere erosion and oncogenic signaling, it has been proposed to play...

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Detalles Bibliográficos
Autores principales: Johmura, Yoshikazu, Nakanishi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132285/
https://www.ncbi.nlm.nih.gov/pubmed/27560979
http://dx.doi.org/10.1111/cas.13060