Cargando…

Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

Apicomplexan parasites contain a conserved protein CelTOS that, in malaria parasites, is essential for traversal of cells within the mammalian host and arthropod vector. However, the molecular role of CelTOS is unknown because it lacks sequence similarity to proteins of known function. Here, we dete...

Descripción completa

Detalles Bibliográficos
Autores principales: Jimah, John R, Salinas, Nichole D, Sala-Rabanal, Monica, Jones, Nathaniel G, Sibley, L David, Nichols, Colin G, Schlesinger, Paul H, Tolia, Niraj H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132341/
https://www.ncbi.nlm.nih.gov/pubmed/27906127
http://dx.doi.org/10.7554/eLife.20621