Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity

Regulation of gene expression in immune cells is known to be under genetic control, and likely contributes to susceptibility to autoimmune diseases, such as multiple sclerosis (MS). How this occurs in concert across multiple immune cell types is poorly understood. Using a mouse model that harnesses...

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Detalles Bibliográficos
Autores principales: Bearoff, Frank, del Rio, Roxana, Case, Laure K., Dragon, Julie A., Nguyen-Vu, Trang, Lin, Chin-Yo, Blankenhorn, Elizabeth P., Teuscher, Cory, Krementsov, Dimitry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133152/
https://www.ncbi.nlm.nih.gov/pubmed/27653816
http://dx.doi.org/10.1038/gene.2016.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133152/
https://www.ncbi.nlm.nih.gov/pubmed/27653816
http://dx.doi.org/10.1038/gene.2016.37

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