Fecal metabolomics in pediatric spondyloarthritis implicate decreased metabolic diversity and altered tryptophan metabolism as pathogenic factors

OBJECTIVE: We have previously shown alterations in the composition of the gut microbiota in children with enthesitis-related arthritis (ERA). To explore the mechanisms by which an altered microbiota might predispose to arthritis, we performed metabolomic profiling of fecal samples of children with E...

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Detalles Bibliográficos
Autores principales: Stoll, Matthew L, Kumar, Ranjit, Lefkowitz, Elliot, Cron, Randy Q, Morrow, Casey D, Barnes, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133160/
https://www.ncbi.nlm.nih.gov/pubmed/27786174
http://dx.doi.org/10.1038/gene.2016.38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133160/
https://www.ncbi.nlm.nih.gov/pubmed/27786174
http://dx.doi.org/10.1038/gene.2016.38

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