HLA Class I and II alleles, heterozygosity and HLA-KIR interactions are associated with rates of genital HSV shedding and lesions

Variation at HLA and KIR loci is associated with the severity of viral infections. To assess associations of genital HSV-2 infection with human HLA and KIR genetic loci, we measured the frequencies of genital HSV DNA detection and of genital lesions in HSV-2 seropositive persons. We followed 267 HSV...

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Detalles Bibliográficos
Autores principales: Magaret, Amalia, Dong, Lichun, John, Mina, Mallal, Simon A., James, Ian, Warren, Terri, Gaudieri, Silvana, Koelle, David M., Wald, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133162/
https://www.ncbi.nlm.nih.gov/pubmed/27853144
http://dx.doi.org/10.1038/gene.2016.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133162/
https://www.ncbi.nlm.nih.gov/pubmed/27853144
http://dx.doi.org/10.1038/gene.2016.42

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