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Transitional B Cells in Early Human B Cell Development – Time to Revisit the Paradigm?
The B cell repertoire is generated in the adult bone marrow by an ordered series of gene rearrangement processes that result in massive diversity of immunoglobulin (Ig) genes and consequently an equally large number of potential specificities for antigen. As the process is essentially random, the ce...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133252/ https://www.ncbi.nlm.nih.gov/pubmed/27994589 http://dx.doi.org/10.3389/fimmu.2016.00546 |