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Intracerebroventricular Catalase Reduces Hepatic Insulin Sensitivity and Increases Responses to Hypoglycemia in Rats
Specialized metabolic sensors in the hypothalamus regulate blood glucose levels by influencing hepatic glucose output and hypoglycemic counterregulatory responses. Hypothalamic reactive oxygen species (ROS) may act as a metabolic signal-mediating responses to changes in glucose, other substrates and...
Autores principales: | Pauliina Markkula, S., Lyons, David, Yueh, Chen-Yu, Riches, Christine, Hurst, Paul, Fielding, Barbara, Heisler, Lora K., Evans, Mark L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133351/ https://www.ncbi.nlm.nih.gov/pubmed/27740870 http://dx.doi.org/10.1210/en.2015-2054 |
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