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A phosphorylation pattern-recognizing antibody specifically reacts to RNA polymerase II bound to exons
The C-terminal domain of RNA polymerase II is an unusual series of repeated residues appended to the C-terminus of the largest subunit and serves as a flexible binding scaffold for numerous nuclear factors. The binding of these factors is determined by the phosphorylation patterns on the repeats in...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133369/ https://www.ncbi.nlm.nih.gov/pubmed/27857068 http://dx.doi.org/10.1038/emm.2016.101 |