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Aldehyde dehydrogenase is used by cancer cells for energy metabolism

We found that non-small-cell lung cancer (NSCLC) cells express high levels of multiple aldehyde dehydrogenase (ALDH) isoforms via an informatics analysis of metabolic enzymes in NSCLC and immunohistochemical staining of NSCLC clinical tumor samples. Using a multiple reaction-monitoring mass spectrom...

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Detalles Bibliográficos
Autores principales: Kang, Joon Hee, Lee, Seon-Hyeong, Hong, Dongwan, Lee, Jae-Seon, Ahn, Hee-Sung, Ahn, Ju-Hyun, Seong, Tae Wha, Lee, Chang-Hun, Jang, Hyonchol, Hong, Kyeong Man, Lee, Cheolju, Lee, Jae-Ho, Kim, Soo-Youl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133370/
https://www.ncbi.nlm.nih.gov/pubmed/27885254
http://dx.doi.org/10.1038/emm.2016.103