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Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants

Mendelian randomization investigations are becoming more powerful and simpler to perform, due to the increasing size and coverage of genome-wide association studies and the increasing availability of summarized data on genetic associations with risk factors and disease outcomes. However, when using...

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Detalles Bibliográficos
Autores principales: Burgess, Stephen, Bowden, Jack, Fall, Tove, Ingelsson, Erik, Thompson, Simon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133381/
https://www.ncbi.nlm.nih.gov/pubmed/27749700
http://dx.doi.org/10.1097/EDE.0000000000000559