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Efficacy and Safety of High-Dose Ivermectin for Reducing Malaria Transmission (IVERMAL): Protocol for a Double-Blind, Randomized, Placebo-Controlled, Dose-Finding Trial in Western Kenya

BACKGROUND: Innovative approaches are needed to complement existing tools for malaria elimination. Ivermectin is a broad spectrum antiparasitic endectocide clinically used for onchocerciasis and lymphatic filariasis control at single doses of 150 to 200 mcg/kg. It also shortens the lifespan of mosqu...

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Detalles Bibliográficos
Autores principales: Smit, Menno R, Ochomo, Eric, Aljayyoussi, Ghaith, Kwambai, Titus, Abong'o, Bernard, Bayoh, Nabie, Gimnig, John, Samuels, Aaron, Desai, Meghna, Phillips-Howard, Penelope A, Kariuki, Simon, Wang, Duolao, Ward, Steve, ter Kuile, Feiko O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133431/
https://www.ncbi.nlm.nih.gov/pubmed/27856406
http://dx.doi.org/10.2196/resprot.6617