Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells

Amyloidogenic protein aggregation impairs cell function and is a hallmark of many chronic degenerative disorders. Protein aggregation is also a major event during acute injury; however, unlike amyloidogenesis, the process of injury-induced protein aggregation remains largely undefined. To provide th...

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Detalles Bibliográficos
Autores principales: Samson, Andre L., Ho, Bosco, Au, Amanda E., Schoenwaelder, Simone M., Smyth, Mark J., Bottomley, Stephen P., Kleifeld, Oded, Medcalf, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133435/
https://www.ncbi.nlm.nih.gov/pubmed/27810968
http://dx.doi.org/10.1098/rsob.160098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133435/
https://www.ncbi.nlm.nih.gov/pubmed/27810968
http://dx.doi.org/10.1098/rsob.160098

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