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Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels

The host immune system offers a hostile environment with antimicrobials and reactive oxygen species (ROS) that are detrimental to bacterial pathogens, forcing them to adapt and evolve for survival. However, the contribution of oxidative stress to pathogen evolution remains elusive. Using an experime...

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Detalles Bibliográficos
Autores principales: Chua, Song Lin, Ding, Yichen, Liu, Yang, Cai, Zhao, Zhou, Jianuan, Swarup, Sanjay, Drautz-Moses, Daniela I., Schuster, Stephan Christoph, Kjelleberg, Staffan, Givskov, Michael, Yang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133437/
https://www.ncbi.nlm.nih.gov/pubmed/27881736
http://dx.doi.org/10.1098/rsob.160162