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SBE6: a novel long-range enhancer involved in driving sonic hedgehog expression in neural progenitor cells

The expression of genes with key roles in development is under very tight spatial and temporal control, mediated by enhancers. A classic example of this is the sonic hedgehog gene (Shh), which plays a pivotal role in the proliferation, differentiation and survival of neural progenitor cells both in...

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Detalles Bibliográficos
Autores principales: Benabdallah, Nezha S., Gautier, Philippe, Hekimoglu-Balkan, Betul, Lettice, Laura A., Bhatia, Shipra, Bickmore, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133441/
https://www.ncbi.nlm.nih.gov/pubmed/27852806
http://dx.doi.org/10.1098/rsob.160197